<b style="">Effect of modified eggs on metabolic syndrome-X induced stress in female wistar rats</b>

Abstract

Metabolic syndrome-X induced stress is prevalent world over and is being managed through pharmacological treatment. There are some dietary components such as Zn, Cu, Mg, Mn, vitamin-E, C and omega-3 fatty acids which have been shown to reduce the severity of stress associated with metabolic syndrome-X. But in the Indian staple diet, there is a big gap between requirement of these dietary components and their availability in food particularly in the patients of metabolic syndrome-X. Keeping this in mind, modified eggs were designed (Patent Application No.2264 Del-2005) and their efficacy on metabolic syndrome-X was studied in female wistar rats. The results of this study revealed that feeding on these eggs mixed diets to metabolic syndrome-X induced rats, a considerable reduction in stress hormone cortisol, total lipids, LDL-c and VLDL-c in the blood, improvement in the sensitivity of insulin leading to reduction in blood glucose and rise in HDL-c and improvement in the mineral status in blood serum and tissues were observed. This data suggests that these modified eggs are effective in reducing the metabolic syndrome-X induced stress.