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Title: Effect of modified eggs on metabolic syndrome-X induced stress in female wistar rats
Authors: Taneja, S K
Mandal, R
Keywords: Blood lipid profile;Zn;Cu;Mg;Modified egg;NIDDM;Obesity;Omega-3 fatty acids;TEM of adrenal gland;Vitamin E;Metabolic syndrome-X
Issue Date: Feb-2007
Publisher: CSIR
IPC Code: Int. cl.8 — A61K 33/00, A61K 35/54, G01N 33/08
Abstract: Metabolic syndrome-X induced stress is prevalent world over and is being managed through pharmacological treatment. There are some dietary components such as Zn, Cu, Mg, Mn, vitamin-E, C and omega-3 fatty acids which have been shown to reduce the severity of stress associated with metabolic syndrome-X. But in the Indian staple diet, there is a big gap between requirement of these dietary components and their availability in food particularly in the patients of metabolic syndrome-X. Keeping this in mind, modified eggs were designed (Patent Application No.2264 Del-2005) and their efficacy on metabolic syndrome-X was studied in female wistar rats. The results of this study revealed that feeding on these eggs mixed diets to metabolic syndrome-X induced rats, a considerable reduction in stress hormone cortisol, total lipids, LDL-c and VLDL-c in the blood, improvement in the sensitivity of insulin leading to reduction in blood glucose and rise in HDL-c and improvement in the mineral status in blood serum and tissues were observed.  This data suggests that these modified eggs are effective in reducing the metabolic syndrome-X induced stress.
Page(s): 22-33
ISSN: 0975-1092 (Online); 0972-592X (Print)
Appears in Collections:NPR Vol.6(1) [January-February 2007]

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