Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/779
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dc.contributor.authorKumar, Rajesh-
dc.contributor.authorJoshi, Y C-
dc.date.accessioned2008-04-07T09:23:44Z-
dc.date.available2008-04-07T09:23:44Z-
dc.date.issued2007-12-
dc.identifier.issn0376-4699-
dc.identifier.urihttp://hdl.handle.net/123456789/779-
dc.description2021-2025en_US
dc.description.abstractChlorination of 5-(2-ethoxyphenyl)-1-methyl-3-propyl-1, 6-dihydro-7H-pyrazolo [4, 3-d] pyrimidin-7-one 1 with POCl₃ affords 5-(2-ethoxyphenyl)-1-methyl-7-chloro-1H-pyrazolo [4, 3-d] pyrimidine 2. Further compound 2 is condensed with different β-diketones / β-ketoesters3a-e, to obtain new β-diketones/ β-ketoesters 4a-e. The synthesized new β-diketones/ β-ketoesters (4a-e) and o-phenylenediamine (o-PDA) gives biologically active 3H-1,5-benzodiazepines 5a-e. All the newly synthesized compounds are characterized by elemental analysis and spectral studies. The compounds 5a-e have been screened for antimicrobial, antifungal and anthelmintic activity.en_US
dc.language.isoen_USen_US
dc.publisherCSIRen_US
dc.sourceIJCB Vol.46B(12) [December 2007]en_US
dc.subjectPyrazolo[4,3-d]pyrimidin-7-oneen_US
dc.subjectβ-diketones/ β-ketoestersen_US
dc.subjectSilica chlorideen_US
dc.subjecto-phenylenediamineen_US
dc.subject3H-1,5-benzodiazepinesen_US
dc.subjectAntimicrobialen_US
dc.subjectAnthelminticen_US
dc.titleSynthesis, spectral studies and biological activity of novel 3H-1,5-benzodiazepine derivativesen_US
dc.typeArticleen_US
Appears in Collections:IJC-B Vol.46B(12) December 2007]

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