Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/7700
Title: Anti-inflammatory, analgesic and anti-lipid peroxidation studies on leaves of <i>Commiphora caudata</i> (Wight & Arn.) Engl.
Authors: Annu, W
Latha, P G
Shaji, J
Anuja, G I
Suja, S R
Sini, S
Shyamal, S
Shine, V J
Shikha, P
Rajasekharan, S
Keywords: Anti-inflammatory
Analgesic
Antioxidant
<i style="">Commiphora caudata</i>
Lipid peroxidation
Issue Date: Mar-2010
Publisher: CSIR
Series/Report no.: <b style=""></b> <b>Int. cl.<sup>8</sup>—</b> A61K 36/00, A61K 36/328, A61K 127/00, A61P 29/00, A61P 39/06
Abstract: The present study investigates the anti-inflammatory and analgesic properties of ethanol extract of leaves of <i style="">Commiphora caudata</i> (Wight & Arn.) Engl. The anti-inflammatory activity was evaluated by carrageenan induced paw oedema in Wistar albino rats and analgesic effect by acetic acid induced writhing assay in Swiss albino mice. Our findings showed that the oral administration of the extract significantly inhibited carrageenan induced paw oedema and acetic acid induced writhing effects and were comparable to standard drugs, Indomethacin and Aspirin, respectively. The extract also showed significant inhibition of FeCl<sub>2</sub>-ascorbic acid stimulated lipid peroxidation in rat liver homogenate <i style="">in vitro</i>. It can therefore, be concluded from the present study that the ethanolic extract of <i style="">C. caudata</i> possesses potent anti-inflammatory and analgesic properties.
Description: 44-48
URI: http://hdl.handle.net/123456789/7700
ISSN: 0976-0512 (Online); 0976-0504 (Print)
Appears in Collections:IJNPR Vol.1(1) [March 2010]

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