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Indian Journal of Natural Products and Resources (IJNPR)
[Formerly Natural Product Radiance (NPR)] >
IJNPR Vol.1 [2010] >
IJNPR Vol.1(1) [March 2010] >
| Title: | Evaluation of anti-inflammatory activity of the pods of Iklil-ul-Malik (Astragalus hamosus Linn.) |
| Authors: | Hakim, A
Tajuddin
Ghufran, A
Nasreen, J |
| Keywords: | Acute inflammation
Anti-inflammatory activity
Astragalus hamosus
Carrageenin
Iklil-ul-Malik
Piroxicam
Unani medicine |
| Issue Date: | Mar-2010 |
| Publisher: | CSIR |
| IPC Code: | Int. cl.8— A61K 36/00, A61K 36/481, A61K 131/00, A61P 29/00 |
| Abstract: |
The effect of test drug Iklil-ul-Malik (Astragalus
hamosus Linn.) was studied in healthy adult
Wistar rats of either sex weighing 150-200 g; animals were divided into 4 groups of 6
animals each. Animals in Group I served as control and was administered with 2
ml/kg distilled water. In Group II standard drug Piroxicam was given in the
dose of 2.8 mg/kg. Animals in Group III and IV were treated with the dose of
0.58 g/kg of aqueous and alcoholic extract of Iklil-ul-Malik, respectively. Inflammation was induced by
Carrageenin injection in rat hind paw. The significant reduction (P<0.01)
was observed after
3 hours of injection. The percentage inhibition in standard and test groups was
found to be 59.43, 52.17 and 54.34 %, respectively.
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| Page(s): | 34-37 |
| ISSN: | 0976-0512 (Online); 0976-0504 (Print) |
| Source: | IJNPR Vol.1(1) [March 2010]
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