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IJNPR Vol.1(1) [March 2010] >


Title: Evaluation of anti-inflammatory activity of the pods of Iklil-ul-Malik (Astragalus hamosus Linn.)
Authors: Hakim, A
Tajuddin
Ghufran, A
Nasreen, J
Keywords: Acute inflammation
Anti-inflammatory activity
Astragalus hamosus
Carrageenin
Iklil-ul-Malik
Piroxicam
Unani medicine
Issue Date: Mar-2010
Publisher: CSIR
IPC CodeInt. cl.8 A61K 36/00, A61K 36/481, A61K 131/00, A61P 29/00
Abstract:  The effect of test drug Iklil-ul-Malik (Astragalus hamosus Linn.) was studied in healthy adult Wistar rats of either sex weighing 150-200 g; animals were divided into 4 groups of 6 animals each. Animals in Group I served as control and was administered with 2 ml/kg distilled water. In Group II standard drug Piroxicam was given in the dose of 2.8 mg/kg. Animals in Group III and IV were treated with the dose of 0.58 g/kg of aqueous and alcoholic extract of Iklil-ul-Malik, respectively. Inflammation was induced by Carrageenin injection in rat hind paw. The significant reduction (P<0.01) was observed after 3 hours of injection. The percentage inhibition in standard and test groups was found to be 59.43, 52.17 and 54.34 %, respectively.
Page(s): 34-37
ISSN: 0976-0512 (Online); 0976-0504 (Print)
Source:IJNPR Vol.1(1) [March 2010]

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