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Title: Antimicrobial studies on the extracts of <i>Cocculus hirsutus</i> Linn. and <i>Hyptis suaveolens</i> Poit.
Authors: Satish, V
Ravichandrian, V D
Gavani, Usha
Paarakh, Padmaa M
Keywords: Antimicrobial activity
<i>Cocculus hirsutus</i>
<i>Hyptis suaveolens</i>
Disc diffusion method
Phytochemical screening
Issue Date: Mar-2010
Publisher: CSIR
Series/Report no.: <b style=""></b> <b style=""> Int. cl.<sup>8</sup>—</b> A61K 36/00, A61P 31/00<b></b> <b></b>
Abstract: Extracts of <i style="">Cocculus hirsutus </i>Linn. and <i style="">Hyptis suaveolens</i> Poit. were screened for their <i style="">in vitro</i> antimicrobial activity by agar disc diffusion method. The antimicrobial activity of petroleum ether, chloroform, methanol and aqueous extracts of the leaves of these plants were studied using <i>Staphylococcus aureus, Listeria monocytogenes,</i> <i>Escherichia coli</i>, <i>Serratia marcescens</i> and <i>Aspergillus flavus </i>as test organisms. Petroleum ether extracts of <i style="">C. hirsutus</i> and <i>H. suaveolens</i> were found to be more effective against <i>Escherichia coli</i> and <i style="">Serratia marcescens</i> and <i style="">Aspergillus flavus</i>, respectively when compared to other extracts of both the plants. Phytochemical screening of the petroleum ether extract of <i style="">C. hirsutus</i> and <i>H. suaveolens</i> revealed the presence of alkaloids and steroids, respectively which suggests that these phytoconstituents may be responsible for their antimicrobial activity.
Description: 49-52
ISSN: 0976-0512 (Online); 0976-0504 (Print)
Appears in Collections:IJNPR Vol.1(1) [March 2010]

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