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Title: Pharmacognostical studies on the leaves of Cocculus hirsutus (Linn.) Diels – Chilahinta, an Ayurvedic drug
Authors: Madhavan, V
Ullah, Mohamed Sajid
Gurudeva, M R
Yoganarasimhan, S N
Keywords: Cocculus hirsutus
Physico-chemical analysis
Alcohol extract
Issue Date: Mar-2010
Publisher: CSIR
Series/Report no.:  Int. cl.8A61K 36/59, A61K 127/00
Abstract: Cocculus hirsutus (Linn.) Diels known as Chilahinta in Ayurveda and Kattu kodi in Siddha is an important medicinal plant belonging to the family Menispermaceae. The leaves are used to treat several diseases like polyuria, fevers, piles and is said to possess aphrodisiac property. The present study provides taxonomical, pharmacognostical and physico-chemical details helpful in laying down standardization and pharmacopoeial parameters. Some diagnostic characters are presence of unicellular ribbon shaped trichome both on lamina and petiole, presence of sunken stomata, excretory sacs in mesophyll. Physico-chemical studies revealed total moisture content (6.67%), total ash (5.07%), acid insoluble ash (0.57%), water soluble ash (0.65%), alcohol soluble extractive (32.63%) and water soluble extractive (26.85%). Ultraviolet analysis exhibited considerable variation and preliminary organic analysis revealed presence of alkaloids, flavonoids, fixed oils, fats, mucilage, glycosides and phytosterols. HPTLC profile of alcoholic extract of leaves gave 16 phytoconstituents.
Description: 38-43
ISSN: 0976-0512 (Online); 0976-0504 (Print)
Appears in Collections:IJNPR Vol.1(1) [March 2010]

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