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Title: Anti-inflammatory, analgesic and anti-lipid peroxidative effects of <i style="">Rhaphidophora pertusa</i> (Roxb.) Schott. and <i style="">Epipremnum pinnatum </i>(Linn.) Engl. aerial parts
Authors: Linnet, A
Latha, PG
Gincy, MM
Anuja, GI
Suja, SR
Shyamal, S
Shine, VJ
Keywords: <i style="">Rhaphidophora pertusa</i>
<i style="">Epipremnum pinnatum</i>
Lipid peroxidation
Traditional medicine
<i style="">Anathipali</i>
Issue Date: Mar-2010
Publisher: CSIR
Series/Report no.: <b style="">Int. cl.<sup>8</sup>—</b>A61K 36/00, A61P 3/06, A61P 29/00.
Abstract: The ethanol extracts of aerial parts of <i style="">Rhaphidophora pertusa</i> (Roxb.) Schott. and <i style="">Epipremnum pinnatum </i>(Linn.) Engl. (Family-Araceae) were evaluated for their anti-inflammatory activity in Wistar albino rats and analgesic effects in Swiss albino mice. Both the species produced significant inhibition of carrageenan-induced rat paw oedema when compared to the standard drug Indomethacin .They also showed a significant inhibition of acetic acid-induced writhing in mice at all the doses studied. The analgesic effect of <i style="">R. pertusa</i> was almost similar to that caused by the standard drug, aspirin. The ethanol extracts also showed significant anti-lipid peroxidant effects <i style="">in vitro</i> in rat liver homogenate. The acute toxicity study indicated that <i style="">R. pertusa</i> and <i style="">E. pinnatum</i> are fairly non-toxic. The results of the present study support the use of <i>R. pertusa</i> in traditional medicine of Kerala as an anti-inflammatory and analgesic agent and <i style="">E. pinnatum</i> may be included in the same category of medicinal plants.
Description: 5-10
ISSN: 0976-0512 (Online); 0976-0504 (Print)
Appears in Collections:IJNPR Vol.1(1) [March 2010]

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