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IJNPR Vol.1(1) [March 2010] >
|Title: ||Anti-inflammatory, analgesic and anti-lipid peroxidative effects of Rhaphidophora pertusa (Roxb.) Schott. and Epipremnum pinnatum (Linn.) Engl. aerial parts|
|Authors: ||Linnet, A|
|Keywords: ||Rhaphidophora pertusa|
|Issue Date: ||Mar-2010 |
|IPC Code: ||Int. cl.8—A61K 36/00, A61P 3/06, A61P 29/00.|
|Abstract: ||The ethanol
extracts of aerial parts of Rhaphidophora pertusa (Roxb.) Schott.
and Epipremnum pinnatum (Linn.) Engl.
(Family-Araceae) were evaluated for their anti-inflammatory activity in Wistar
albino rats and analgesic effects in Swiss albino mice. Both the species
produced significant inhibition of carrageenan-induced rat paw oedema when
compared to the standard drug Indomethacin .They also showed a significant
inhibition of acetic acid-induced writhing in mice at all the doses studied.
The analgesic effect of R. pertusa
was almost similar to that caused by the standard drug, aspirin. The ethanol
extracts also showed significant anti-lipid peroxidant effects in vitro in rat liver homogenate. The
acute toxicity study indicated that R.
pertusa and E. pinnatum are fairly
non-toxic. The results of the present study support the use of R. pertusa
in traditional medicine of Kerala as an anti-inflammatory and analgesic agent
and E. pinnatum may be included in
the same category of medicinal plants.|
|ISSN: ||0976-0512 (Online); 0976-0504 (Print)|
|Source:||IJNPR Vol.1(1) [March 2010]|