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Title: Drug carrier systems for anticancer agents: A review
Authors: Chadha, Renu
Kapoor, V K
Thakur, Deepika
Kaur, Rupinder
Arora, Poonam
Jain, D V S
Keywords: Anticancer agents;Cyclodextrin;Liposomes;Nanoparticles;Polymers;Solubility
Issue Date: Mar-2008
Publisher: CSIR
Abstract: Poor aqueous solubility and adverse effects in cancer treatment using cytotoxicity or hormone therapy are frequently encountered during formulation and usage of conventional drugs. This paper reviews application of various solubilizers and carriers (polymers, cyclodextrins, dendrimers and proteins and amino acids) being used for improving therapeutic efficacy of these agents. Preparation of microspheres, microcapsules and nanospheres to improve aqueous solubility, and potential of liposomes and nanoparticles as effective drug delivery tools have been discussed.
Page(s): 185-197
ISSN: 0022-4456
Appears in Collections:JSIR Vol.67(03) [March 2008]

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