|
NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR) >
NISCAIR PUBLICATIONS >
Research Journals >
Indian Journal of Experimental Biology (IJEB) >
IJEB Vol.48 [2010] >
IJEB Vol.48(04) [April 2010] >
| Title: | Modulation of cell surface architecture in gastrulating chick embryo in response to altered fibroblast growth factor (FGF) signaling |
| Authors: | Borgave, Seema
Ghaskadbi, Surendra |
| Keywords: | Altered FGF signaling
Cell surface architecture
Chick embryo |
| Issue Date: | Apr-2010 |
| Publisher: | CSIR |
| Abstract: | Gastrulation is a fundamental process that
results in formation of the three germ layers in an embryo. It involves highly
coordinated cell migration. Cell to cell communication through cell surface and
the surrounding molecular environment governs cell migration. In the present
work, cell surface features, which are indicative of the migratory status of a
cell, of an early gastrulating chick embryo were studied using scanning
electron microscopy. The distinct ultrastructural features of cells located in
the various regions of the epiblast are described. Differences in the surface
features of cells from distinct embryonic regions indicate differences in their
migratory capacities. Further, the dynamic nature of these cell surface
features by their response to altered fibroblast growth factor (FGF) signaling,
experimentally created by using either excess FGF or inhibition of FGF signaling
are demonstrated. |
| Page(s): | 346-353 |
| ISSN: | 0975-1009 (Online); 0019-5189 (Print) |
| Source: | IJEB Vol.48(04) [April 2010]
|
|
