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Title: Al₂O₃ catalyzed Friedlander synthesis of 1, 8-naphthyridines in the solid state
Authors: Mogilaiah, K
Vidya, K
Keywords: Friedlander synthesis;1,8-naphthyridines;Al₂O₃;2-aminonicotin-aldehyde;Carbonyl compounds containing ⍺-methylene group;Solid state
Issue Date: Oct-2007
Publisher: CSIR
Abstract: Al₂O₃ catalyzes efficiently the Freidlander condensation of 2-aminonicotinaldehyde 1 with various carbonyl compounds containing ⍺-methylene group 2 in the solid state to afford the corresponding 1,8-naphthyridines 3. The reaction proceeds efficiently at room temperature in good yields and in a state of high purity.
Page(s): 1721-1723
ISSN: 0376-4699
Appears in Collections:IJC-B Vol.46B(10) [October 2007]

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