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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.49B [2010] >
IJC-B Vol.49B(03) [March 2010] >
| Title: | Improved synthesis of chalcones and pyrazolines under ultrasonic irradiation |
| Authors: | Gupta, Ragini
Gupta, Neetu
Jain, Anshu |
| Keywords: | Chalcones
2-pyrazolines
Claisen-Schmidt condensation
sonochemistry
antimicrobial |
| Issue Date: | Mar-2010 |
| Publisher: | CSIR |
| Abstract: |
Five
1,3-diarylprop-2-en-1-ones 3a-e are
synthesized by Claisen-Schmidt condensation of aryl methyl ketones and
4-chlorobenzaldehyde to give pyrazolines 5a-e
by cyclization with phenylhydrazine in gl. acetic acid using ultrasonic
irradiation in lesser time with higher yields. All the synthesized compounds
are characterized by elemental analyses and spectral data IR, PMR and are
screened for their antimicrobial activities. Some of them have shown promising
results against E. coli, S. aureus, C. albicans and A. niger.
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| Page(s): | 351-355 |
| Source: | IJC-B Vol.49B(03) [March 2010]
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