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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.46B [2007] >
IJC-B Vol.46B(10) [October 2007] >
| Title: | Clay-catalyzed high-speed synthesis of thiadiazepine in one-pot |
| Authors: | Siddiqui, Ibadur R Singh, Pravin K Srivastava, Vishal Singh, J |
| Keywords: | Clay-catalyzed Microwave irradiation Fungicide Thiadiazepine Green chemical process Multi-steps reactions |
| Issue Date: | Oct-2007 |
| Publisher: | CSIR |
| Abstract: | Microwave assisted clay-catalyzed solid state integrated chemical process which enables the consumption of toxic inter-mediates and their isolation from environment, reduce reaction time, cost and complex isolation procedures enhances yields are effective for realizing a green chemical process in library synthe-ses of bio-active compounds. This is described here in the synthe-sis of thiadiazepine. Antifungal screening results on Fusarium oxysporum and Penicillium citrinum show that most of the syn-thesized compounds display promising antifungal activity, compa-rable with griseofulvin and dithane M-45 as standards. |
| Page(s): | 1716-1720 |
| ISSN: | 0376-4699 |
| Source: | IJC-B Vol.46B(10) [October 2007]
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