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Title: Lewis-acid mediated acetamidation of N-protected bromomethylindoles
Authors: Dhayalan, Vasudevan
Mohanakrishnan, Arasambattu K
Keywords: Bromomethylindole;Lewis acid;acetamidation;aminomethylindoles
Issue Date: Mar-2010
Publisher: CSIR
Abstract: A facile ZnBr2-mediated acetamidation of various types of N-protected 2/3-bromomethylindoles is reported. Upon interaction of bromomethylindoles with acetonitrile in the presence of anhydrous ZnBr2 at reflux followed by aqueous work up led to the isolation of respective acetamidomethylindoles in good yields.
Page(s): 327-334
Appears in Collections:IJC-B Vol.49B(03) [March 2010]

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