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IJC-B Vol.49B [2010] >
IJC-B Vol.49B(03) [March 2010] >


Title: Microwave enhanced, solvent free green protocol for the production of 3,4-dihydropyrimidine-2-(1H)-ones using AlCl3.6H2O as a catalyst
Authors: Kumar, Dhruva
Sandhu, Jagir S
Keywords: 3,4-Dihydropyrimidine-2-(1H)-ones
aldehyde
urea or thiourea
1,3-dicarbonyl compounds
AlCl3.6H2O
microwave
multicomponent reaction
Issue Date: Mar-2010
Publisher: CSIR
Abstract: 3,4-Dihydropyrimidine-2-(1H)-ones are synthesized via a multicomponent reaction of aldehyde, urea or thiourea and 1,3-dicarbonyl compounds using microwave irradiation catalyzed by 10 mol% AlCl3.6H2O under solvent-free conditions. The catalyst being reported here is cheap, safe to handle and the whole procedure is eco-friendly.
Page(s): 360-363
Source:IJC-B Vol.49B(03) [March 2010]

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