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http://nopr.niscair.res.in/handle/123456789/7466
Title: | Protective effect of resveratrol and vitamin E against ethanol-induced oxidative damage in mice: Biochemical and immunological basis |
Authors: | Das, Subir Kumar Mukherjee, Sukhes Gupta, Geetanjali Rao, D N Vasudevan, D M |
Keywords: | Cytokines;Ethanol;Oxidative stress;Resveratrol;Vitamin E |
Issue Date: | Feb-2010 |
Publisher: | CSIR |
Abstract: | The metabolism of ethanol gives rise to the generation of excess amounts of reactive oxygen species and is also associated with immune dysfunction. We examined the efficacy of resveratrol and vitamin E on the immunomodulatory activity and vascular function in mice with liver abnormalities induced by chronic ethanol consumption by measuring the protein, liver-specific transaminase enzymes, antioxidant enzymes and non-enzymes such as reduced glutathione (GSH) content, thiobarbituric acid reactive substance (TBARS) level, nitrite level, and activities of superoxide dismutase (SOD), catalase (CAT), glutathione reductase (GR) and glutathione peroxidase (GPx) and glutathione-S-transferase (GST), and cytokines such as interleukin (IL)-2, IL-4, IL-10, tumor necrosis factor (TNF)-![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
Page(s): | 32-37 |
URI: | http://hdl.handle.net/123456789/7466 |
ISSN: | 0975-0959 (Online); 0301-1208 (Print) |
Appears in Collections: | IJBB Vol.47(1) [February 2010] |
Files in This Item:
File | Description | Size | Format | |
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IJBB 47(1) 32-37.pdf | 89.35 kB | Adobe PDF | View/Open |
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