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Indian Journal of Experimental Biology (IJEB) >
IJEB Vol.48 [2010] >
IJEB Vol.48(03) [March 2010] >
| Title: | Impact of natural products in modern drug development |
| Authors: | Dev, Sukh |
| Keywords: | ACE inhibitors
Anticancer drugs
Antihypertension drugs
Drug discovery
Phytopharmaceuticals |
| Issue Date: | Mar-2010 |
| Publisher: | CSIR |
| Abstract: | Usage of natural substances as therapeutic
agents in modern medicine has sharply declined from the predominant position
held in the early decades of last century, but search for bioactive molecules
from nature (plants, animals, microflora) continues to play an important role
in fashioning new medicinal agents. With the advent of modern techniques, instrumentation
and automation in isolation and structural characterisation, we have on hand an
enormous repository of natural compounds. In parallel to this, biology has also
made tremendous progress in expanding its frontiers of knowledge. An interplay of
these two disciplines constitutes the modern thrust in research in the realm of
compounds elaborated by nature. The purpose of this article is to underline how
natural products research continues to make significant contributions in the
domain of discovery and development of new medicinal products. It is proposed
to present the material under several heads, each of which has made natural
products research relevant in the search for new and better medication. |
| Page(s): | 191-198 |
| ISSN: | 0975-1009 (Online); 0019-5189 (Print) |
| Source: | IJEB Vol.48(03) [March 2010]
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