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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.49B [2010] >
IJC-B Vol.49B(02) [February 2010] >
| Title: | A new route for the synthesis of (R)-glyceraldehyde acetonide: A key chiral building block |
| Authors: | Babu, K Chandra
Ramadasu, G
Gangaiah, L
Madhusudhan, G
Mukkanti, K |
| Keywords: | (R)-Glyceraldehyde acetonide
asymmetric dihydroxylation
allyl 4-methoxybenzoate
chiral building block
Swern oxidation |
| Issue Date: | Feb-2010 |
| Publisher: | CSIR |
| Abstract: | A new route for the synthesis of (R)-glyceraldehyde acetonide via asymmetric dihydroxylation of allyl 4-methoxybenzoate using the (DHQ)2PHAL, K2OsO4·2H2O catalyst system is described. This route involves the asymmetric dihydroxylation of allyl 4-methoxybenzoate, acetonide protection of vicinyl dihydroxyl groups followed by cleavage of p-methoxybenzoate ester and subsequent oxidation to give the (R)-glyceraldehyde acetonide. |
| Page(s): | 260-263 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Source: | IJC-B Vol.49B(02) [February 2010]
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