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IJC-B Vol.49B(02) [February 2010] >


Title: Synthesis and antibacterial activities of some novel isoxazolidine derivatives derived from N-phenyl--chloro nitrone in water
Authors: Chakraborty, Bhaskar
Chhetri, Manjit Singh
Kafley, Saurav
Samanta, Amalesh
Keywords: N-Phenyl--chloro nitrone
1,3 DCR
aqueous phase
stereoselectivity
regioselectivity
antimicrobial activity
Issue Date: Feb-2010
Publisher: CSIR
Abstract: 1,3 Dipolar cycloaddition reaction of N-phenyl--chloro nitrone with different dipolarophiles have been studied in water for the synthesis of novel isoxazolidines. Significant rate acceleration and high yield of these reactions are observed in water with remarkable changes in stereo and regioselectivity compared to organic solvents. The structures of all compounds have been established on the basis of spectral and analytical data. All compounds have been screened for their antibacterial activity and found to be active.
Page(s): 209-215
ISSN: 0975-0983(Online); 0376-4699(Print)
Source:IJC-B Vol.49B(02) [February 2010]

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