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|Title:||Synthesis and antibacterial activities of some novel isoxazolidine derivatives derived from N-phenyl--chloro nitrone in water|
Chhetri, Manjit Singh
|Keywords:||N-Phenyl--chloro nitrone;1,3 DCR;aqueous phase;stereoselectivity;regioselectivity;antimicrobial activity|
|Abstract:||1,3 Dipolar cycloaddition reaction of N-phenyl--chloro nitrone with different dipolarophiles have been studied in water for the synthesis of novel isoxazolidines. Significant rate acceleration and high yield of these reactions are observed in water with remarkable changes in stereo and regioselectivity compared to organic solvents. The structures of all compounds have been established on the basis of spectral and analytical data. All compounds have been screened for their antibacterial activity and found to be active.|
|Appears in Collections:||IJC-B Vol.49B(02) [February 2010]|
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