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Title: Enantioselective synthesis of diarylmethanols using microbial transformation
Authors: Salokhe, P R
Rashinkar, G S
Salunkhe, R S
Keywords: Enantioselective reduction
diaryl ketones
microbial transformation
<i style="">Rhizopus arrhizus</i>
Issue Date: Feb-2010
Publisher: CSIR
Abstract: Enantioselective synthesis of diarylmethanols by microbial reduction of corresponding diaryl ketones has been reported through various strains of <i style="">Rhizopus arrhizus</i>. The various physicochemical parameters for the bioreduction of diaryl ketones were optimized by taking <i style="">p</i>-chloro benzophenone as a model substrate. In order to study the potentiality of the microbe, the bioreduction of <i style=""><img src='/image/spc_char/alpha.gif' border=0>,<img src='/image/spc_char/beta.gif' border=0></i>-unsaturated diaryl ketones <i style="">viz.</i> chalcones have been studied.
Description: 199-202
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.49B(02) [February 2010]

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