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dc.contributor.authorGaikwad, Kishor V-
dc.contributor.authorGaikwad, Sandip V-
dc.contributor.authorJadhav, Satish B-
dc.contributor.authorRathod, Shantilal D-
dc.identifier.issn0975-0983(Online); 0376-4699(Print)-
dc.description.abstractA new series of methyl-2-[substituted benzylidine]-4-[2-(ph­thalimide) ethoxy] acetoacetate, 5a-h have been synthesized from the combination of methyl-4-[2-(phthalimido) ethoxy] aceto­acetate, 3 and substituted benzaldehyde 4a-h which results in both anti-inflammatory and antimicrobial active compound. These compounds have been characterized by IR, 1H NMR, mass spectral and elemental analysis. These compounds have been subjected to preliminary anti-inflammatory screening using the carrageenan induced rat pow oedema model. Compounds 5a,b,c show marked activity comparable to indomethacin. Compounds 5a,b,c,g show significant antimicrobial activity.en_US
dc.sourceIJC-B Vol.49B(01) [January 2010]en_US
dc.subjectEster of phthalimidesen_US
dc.subjectanti-inflammatory and antimicrobial activityen_US
dc.titleSynthesis of some novel chalcones of phthalimidoester possessing good anti-inflammatory and antimicrobial activityen_US
Appears in Collections:IJC-B Vol.49B(01) [January 2010]

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