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|Title:||Scalable synthesis of 3,4-dihydropyrimidin-2(1H)-ones under solvent free condition|
|Keywords:||Iodine;Aldehyde;Ethyl acetoacetate;Urea;Dihydropyrimidin-2(1H)-one;Solvent free condition|
|Abstract:||An improved solvent free, one pot procedure for the synthesis of 5-ethoxycarbonyl-4-aryl-3,4-dihydropyrimidin-2(1H)-ones catalyzed by iodine is developed. The process has been utilized successfully in large-scale synthesis of Biginelli products.|
|ISSN:||0975-0991 (Online); 0971-457X (Print)|
|Appears in Collections:||IJCT Vol.13(5) [September 2006]|
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