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Indian Journal of Experimental Biology (IJEB) >
IJEB Vol.44 [2006] >
IJEB Vol.44(11) [November 2006] >
| Title: | Effect of ovine follicular fluid peptide on ovarian responses and other organ weights in rats, Rattus norvegicus Berkenhout 1769 |
| Authors: | Nandi, S
Kumar, V Girish
Gupta, P S P |
| Keywords: | Follicular fluid
In vivo
Ovarian responses
Peptide |
| Issue Date: | Nov-2006 |
| Publisher: | CSIR |
| Abstract: | The present study was aimed to study the
effect of an ovine follicular fluid peptide on ovarian follicle and good oocyte
numbers and weights of ovary, uterus, liver, pancreas and kidney in rats, R. norvegicus. A 30.1 kDa peptide was
isolated from ovine follicular fluid by ammonium sulphate precipitation and
then gel filtration. The peptide was tested at various levels in normal (22 and
36 day-old), superovulated (29 day-old) immature and 121-day old mature rats on
the ovarian responses and other organ weights. The isolated peptide inhibited
the growth of antral follicles in normal and superovulated rats. Ovarian,
uterine weight and recovery of good oocytes were reduced when the peptide was
administered at 100 mg dose.
The peptide had no effect on kidney, liver, pancreas weight and recovery of
preantral follicles. |
| Page(s): | 880-885 |
| ISSN: | 0975-1009 (Online); 0019-5189 (Print) |
| Source: | IJEB Vol.44(11) [November 2006]
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