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Research Journals >
Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.46B [2007] >
IJC-B Vol.46B(08) [August 2007] >
| Title: | Pyrrolidine catalyzed regioselective and diastereoselective direct aldol reaction in water |
| Authors: | Mahajan, Dinesh
Chimni, Swapandeep Singh |
| Keywords: | Direct aldol reaction
Pyrrolidine catalysis
Regioselective synthesis
Diastereoselective synthesis
Aqueous media
Organocatalysis |
| Issue Date: | Aug-2007 |
| Publisher: | CSIR |
| Abstract: | Pyrrolidine catalyzed direct aldol reaction of methyl ketones other than acetone with 4-nitrobenzaldehyde in water affords linear aldol addition product arising from the selective attack of the unsubstituted carbon of the unsymmetrical ketone. The present methodology provides an experimentally simple and green process for regioselective synthesis of -hydroxyketones in water. |
| Page(s): | 1355-1358 |
| ISSN: | 0376-4699 |
| Source: | IJC-B Vol.46B(08) [August 2007]
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