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Title: Trans-differentiation of iris pigmented epithelial cells of <i style="">Euphlyctis cyanophlyctis</i> tadpoles into lens <i style="">in vitro</i>
Authors: Sharma, Manshi
Jangir, O P
Jhajharia, Sunita
Singh, Sumer
Singh, Vijay
Nagal, Amit
Keywords: Frog
Pigmented epithelial cells
Issue Date: Jan-2010
Publisher: CSIR
Abstract: Meshed pigmented iris epithelium along with neural retina of tadpoles of the frog <i style="">Euphlyctis</i> <i style="">cyanophlyctis</i> were found to undergo dedifferentiation and subsequently transdifferentiate into lens in culture medium. During lag period, depigmentation (dedifferentiation) occurred in many cells. When culture became confluent 3-4 weeks after seeding tiny lens like structures differentiated from foci of cultured pigmented iris epithelium cells. The percentage of lens formation was higher in vitamin A treated cases. The culture system appears to be a suitable for investigating the changes occurred during trans-differentiation of pigmented epithelial cells into lens.
Description: 17-25
ISSN: 0975-1009 (Online); 0019-5189 (Print)
Appears in Collections:IJEB Vol.48(01) [January 2010]

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