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Title: Adventures in heterocycle chemistry: The oxa-Michael cascade for the synthesis of complex natural products and highly functionalized bioactive compounds
Authors: Volz, N
Bröhmer, M C
Toräng, J
Nieger, M
Bräse, S
Keywords: Oxygen-heterocycles
domino oxa-Michael-Aldol reaction
natural products
Issue Date: Dec-2009
Publisher: CSIR
Abstract:  This is an account of the award lecture given by Stefan Bräse on the occasion of the ISCB AWARD FOR EXCELLENCE 2009 of the Indian Society of Chemical Biologists, held in Delhi in January 2009. The domino reaction between salicylaldehydes and α,β-unsaturated aldehydes is a common method to obtain a great variety of oxygen-heterocycles like cannabinoids, chromenes, and coumarins. This reaction enables also the synthesis of mycotoxins such as diversonol, the blennolides and secalonic acids.
Description: 1699-1703
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.48B(12) December 2009]

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