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IJC-B Vol.46B [2007] >
IJC-B Vol.46B(07) [July 2007] >
| Title: | Synthesis of some 4-substituted hydrazinotetrazolo[1,5-⍺] quinoxalines |
| Authors: | Deshmukh, M B
Mali, A R
Jadhav, S D
Suryawanshi, A W |
| Keywords: | Quinoxaline
NMDA receptor
Biological activity |
| Issue Date: | Jul-2007 |
| Publisher: | CSIR |
| Abstract: | Reaction of 2,3 diketoquinoxaline in presence of phosphorus pentachloride and sodium azide in methanol gives 4-hydroxy tetrazolo[1,5-⍺]quinoxaline 3 which on reaction with phosphorous oxychloride gives 4-chloro tetrazolo[1,5-⍺]quinoxaline 4. This on treatment with hydrazine hydrate in ethanol yields 4-hydrazino tetrazolo[1,5-⍺]quinoxaline 5, which on reaction with various aldehydes in DMF gives 4-substituted hydrazinotetrazolo [1,5-⍺]quinoxalines 6a-g. The structures of compounds 6a-g have been confirmed by IR and ¹H NMR. |
| Page(s): | 1211-1213 |
| ISSN: | 0376-4699 |
| Source: | IJC-B Vol.46B(07) [July 2007]
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