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Title: Synthesis of some 4-substituted hydrazinotetrazolo[1,5-⍺] quinoxalines
Authors: Deshmukh, M B
Mali, A R
Jadhav, S D
Suryawanshi, A W
Keywords: Quinoxaline;NMDA receptor;Biological activity
Issue Date: Jul-2007
Publisher: CSIR
Abstract: Reaction of 2,3 diketoquinoxaline in presence of phosphorus pentachloride and sodium azide in methanol gives 4-hydroxy tetrazolo[1,5-⍺]quinoxaline 3 which on reaction with phosphorous oxychloride gives 4-chloro tetrazolo[1,5-⍺]quinoxaline 4. This on treatment with hydrazine hydrate in ethanol yields 4-hydrazino tetrazolo[1,5-⍺]quinoxaline 5, which on reaction with various aldehydes in DMF gives 4-substituted hydrazinotetrazolo [1,5-⍺]quinoxalines 6a-g. The structures of compounds 6a-g have been confirmed by IR and ¹H NMR.
Page(s): 1211-1213
ISSN: 0376-4699
Appears in Collections:IJC-B Vol.46B(07) [July 2007]

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