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Research Journals >
Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.45B [2006] >
IJC-B Vol.45B(12) December 2006] >
| Title: | An enantiospecific strategy to all four diastereomers of A-ring enyne synthon of 1 ,25-dihydroxyvitamin D3 |
| Authors: | Srikrishna, A
Gharpure, Santosh J
Kumar, P Praveen |
| Keywords: | Vitamin D3
calcitriol
Criegee rearrangement
A-ring enyne synthon
carvone |
| Issue Date: | Dec-2006 |
| Publisher: | CSIR |
| IPC Code: | Int Cl.8 C07C |
| Abstract: | Enantiospecific syntheses of derivatives all the four diastereomers of A-ring enyne synthon of 1,25-dihydroxyvitamin D3 (5-ethynyl-4-methylcyclohex-4-en-1,3-diol) have been described starting from the abundantly available monoterpene (R)-carvone, exploiting the isopropenyl group of carvone as an equivalent of an hydroxy group. A combination of Criegee rearrangement and Mitsunobu reactions has been strategically employed. |
| Page(s): | 2736-2744 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Source: | IJC-B Vol.45B(12) December 2006]
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