Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/6776
Title: A facile [hydroxy(tosyloxy)iodo]benzene mediated synthesis of 2-arylimidazo[1,2-<i><img src='/image/spc_char/alpha.gif' border=0></i>]pyrimidines and their conversion into 3-bromo-2-arylimidazo[1,2-<i><img src='/image/spc_char/alpha.gif' border=0></i>]pyrimidines
Authors: Aggarwal, Ranjana
Sumran, Garima
Keywords: <img src='/image/spc_char/alpha.gif' border=0> -Tosyloxyketones
[hydroxy(tosyloxy)iodo]benzene
2-arylimidazo[1,2-<i><img src='/image/spc_char/alpha.gif' border=0></i>]pyrimidines
electrophilic substi­tution, 3-bromo-2-arylimidazo[1,2-<i><img src='/image/spc_char/alpha.gif' border=0> </i>]pyrimidines
Issue Date: Dec-2006
Publisher: CSIR
Series/Report no.: Int. Cl.<sup>8</sup> C07D
Abstract: <img src='/image/spc_char/alpha.gif' border=0>-Tosyloxyketone <b style="">2</b>, obtained through hypervalent iodine oxidation of enolizable ketones using [hydroxy(tosyloxy)iodo]benzene (HTIB) in acetonitrile, on treatment with 2-aminopyrimidine <b style="">3</b> generates regioselectively 2-arylimidazo[1,2-<i><img src='/image/spc_char/alpha.gif' border=0> </i>]pyrimidine <b style="">6</b> which upon subsequent treatment with bromine undergoes electrophilic substitution at position-3 to yield 3-bromo-2-arylimidazo[1,2-<i><img src='/image/spc_char/alpha.gif' border=0> </i>]pyrimidine <b style="">8</b>.
Description: 2690-2695
URI: http://hdl.handle.net/123456789/6776
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.45B(12) December 2006]

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