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Title: Correlation between the <i style="">p</i>Ka and pharmacological properties of some imidazolin-5(4<i style="">H</i>)-ones, their precursors and Schiff’s bases
Authors: Gupta, J K
De, Biplab
Saravanan, V S
Keywords: Imidazolin-5(4<i style="">H</i>)-ones
Schiff bases
potentiometric method
analgesic activity
CNS depressant property
Issue Date: Nov-2006
Publisher: CSIR
Series/Report no.: Int. Cl.<sup>8</sup> C07D
Abstract: The <i style="">p</i>Ka value of some synthesized imidazolin-5(4<i style="">H</i>)-ones and their precursors, Schiff’s bases are determined by potentiometric method and the analgesic activity and CNS depressant property are evaluated, which are correlated with the <i style="">p</i>Ka values. It is found that a correlation established in best fit curve of 3<sup>rd</sup> order polynomial equation.
Description: 2580-2582
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.45B(11) [November 2006]

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