Please use this identifier to cite or link to this item:
|Title:||Asymmetric induction in copper (I)-catalyzed intramolecular [2 + 2] photocycloaddition: Synthesis of enantiopure cyclobutane derivatives|
|Series/Report no.:||Int. Cl.8 C07C|
|Abstract:||A simple approach for asymmetric induction in copper (I)-catalyzed intramolecular [2 + 2] photocycloaddition of 1,6-dienes, where asymmetric catalysis or chiral auxiliaries have been inefficient, has been developed using the concept of chirality transfer from the readily available 2,3-di-O-cyclohexylidine–(R)-(+)-glyceraldehyde to produce enantiopure oxa-bicyclo[3.2.0]heptane derivatives. A novel anion-induced cleavage of the tetrahydrofuran ring in these oxa-bicyclo[3.2.0]heptane derivatives has led to a convenient access to the synthetically useful cis-1,2-disubstituted cyclobutanes in enantiomerically pure form.|
|Appears in Collections:||IJC-B Vol.45B(11) [November 2006]|
Files in This Item:
|IJCB 45B(11) 2474-2484.pdf||108.46 kB||Adobe PDF||View/Open|
Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.