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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.45B [2006] >
IJC-B Vol.45B(11) [November 2006] >
| Title: | Synthesis, insecticidal and antimicrobial activities of some heterocyclic derivatives of quinazolinone |
| Authors: | Singh, Tripti
Sharma, Shalabh
Srivastava, Virendra Kishore
Kumar, Ashok |
| Keywords: | Triazinoquanizolinone
Periplaneta americana
insecticidal acitivity
antifungal
antibacterial activity |
| Issue Date: | Nov-2006 |
| Publisher: | CSIR |
| IPC Code: | Int. Cl.8 C07D |
| Abstract: | Some new 4-phenyl-2,3-dihydro-6-(substitutedaminoethyl)-10-iodo[1,2,4]-triazino[2,3-c]-quina-zolin-5-ones 6-14 have been synthesized from 4-(phenyl-2,3-dihydro-6-methyl-10-iodo [1,2,4]-triazino[2,3-c]quinazolin-5-one 5 by introducing different heterocyclic nuclei. Compounds 5 and 6-14 have been screened for insecticidal, anti-fungal and antibacterial activities. Compound 4-phenyl-2, 3-dihydro-6-(b-naphthylaminoethyl)-10-iodo[1, 2, 4]-triazino[2,3-c]-quinazolin-5-one 14 has been found to be the most potent compound of the present study which shows mortality of insects at 190.6 min while standard compounds exhibit at 280 min at a concentration of 5 g/L. Moreover, this compound also possesses anti-bacterial activity. The structures of these compounds have been elucidated by IR, 1H NMR, mass spectroscopy and elemental analysis. |
| Page(s): | 2558-2565 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Source: | IJC-B Vol.45B(11) [November 2006]
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