Please use this identifier to cite or link to this item:
Full metadata record
DC FieldValueLanguage
dc.contributor.authorReddy, Pulimamidi R-
dc.contributor.authorRaju, Nomula-
dc.contributor.authorReddy, Karnati V-
dc.identifier.issn0975-0975(Online); 0376-4710(Print)-
dc.description.abstractReaction of copper(II) with tryptophan-tryptophan yields a 1:2 chloro bis(trp-trp) cuprate(II) complex. The complex exhibits absorption band at 620 nm (ε = 130 M -1 cm-1), which suggests a square pyramidal geometry at Cu(II) as observed for other Cu(II)-peptide complexes. The giso value of 2.09 for the complex agrees with a Cu(II) environment of distorted square pyramidal geometry. The mononuclear complex binds to calf thymus DNA through moderate intercalative and weak covalent interactions. It converts the supercoiled plasmid pUC19 DNA to the nicked circular form under physiological conditions.en_US
dc.relation.ispartofseriesInt. Cl.9 C07C229/76; C07F1/08en_US
dc.sourceIJC-A Vol.48A(12) [December 2009]en_US
dc.subjectCoordination chemistryen_US
dc.subjectAmino acidsen_US
dc.subjectThermal denaturationen_US
dc.subjectDNA quenchingen_US
dc.subjectDNA cleavageen_US
dc.titleSynthesis, characterization and DNA binding and cleavage properties of copper(II)-tryptophan-tryptophan complexen_US
Appears in Collections:IJC-A Vol.48A(12) [December 2009]

Files in This Item:
File Description SizeFormat 
IJCA 48A(12) 1638-1643.pdf208.32 kBAdobe PDFView/Open

Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.