NISCAIR Online Periodicals Repository

Research Journals >
Indian Journal of Experimental Biology (IJEB) >
IJEB Vol.47 [2009] >
IJEB Vol.47(12) [December 2009] >

Title: Anxiolytic effect of hydroethanolic extract of Drymaria cordata L Willd
Authors: Barua, Chandana C
Roy, Jayanti D
Buragohain, Bhaben
Barua, Achinta G
Borah, Prabodh
Lahkar, Mangala
Keywords: Anxiolytic effect
Drymaria cordata
Issue Date: Dec-2009
Publisher: CSIR
Abstract: Drymaria cordata hydroethanolic extract (DCHE) at 25, 50 and 100 mg/kg (po) was administered to study anxiolytic effect. Different models for anxiolytic activity viz. Hole board, Open field, Elevated plus maze, Light/dark exploration model were used. In the hole board model, there was dose dependent and significant increase in the numbers of head pokes and the time of head dipping in the treated groups in comparison to the vehicle. In open field test, the number of rearing, assisted rearing and numbers of squares traversed increased significantly. Similarly, in elevated plus maze test, there was significant increase in the time spent and number of entries in open arm as compared to the time spent and number of entries in closed arm in dose dependent manner. In light/dark exploration test, another model for anxiolytic activity, the time spent in lit box , number of crossing and the latency period increased significantly with reduction in time spent in dark box after treatment with DCHE. The presence of phytochemicals viz. triterpenes, diterpenes, steroids and tannins might contribute to its anxiolytic activity.
Page(s): 969-973
ISSN: 0975-1009 (Online); 0019-5189 (Print)
Source:IJEB Vol.47(12) [December 2009]

Files in This Item:

File Description SizeFormat
IJEB 47(12) 969-973.pdf200.32 kBAdobe PDFView/Open
 Current Page Visits: 80 
Recommend this item


Online Submission of Articles |  NISCAIR Website |  National Knowledge Resources Consortium |  Contact us |  Feedback

Disclaimer: NISCAIR assumes no responsibility for the statements and opinions advanced by contributors. The editorial staff in its work of examining papers received for publication is helped, in an honorary capacity, by many distinguished engineers and scientists.

CC License Except where otherwise noted, the Articles on this site are licensed under Creative Commons License: CC Attribution-Noncommercial-No Derivative Works 2.5 India

Copyright © 2015 The Council of Scientific and Industrial Research, New Delhi. All rights reserved.

Powered by DSpace Copyright © 2002-2007 MIT and Hewlett-Packard | Compliant to OAI-PMH V 2.0

Home Page Total Visits: 164675 since 01-Sep-2015  Last updated on 21-Jun-2016Webmaster: