Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/6695
Title: Manufacture of therapeutic oligonucleotides: Development of new reagents and processes
Authors: Sinha, Nanda D
Kuchimanchi, Satya N
Miranda, Greg
Shaikh, Saied
Keywords: Oligonucleotides
manufacture
antisense
RNAi (RNA interfererence)
aptamer
green chemistry
Issue Date: Oct-2006
Publisher: CSIR
Series/Report no.: Int.Cl.<sup>8</sup>C07D
Abstract: The optimization of synthesis, purification process parameters and development of new reagents have enabled successful large-scale manufacture of several therapeutic grade oligonucleotides at Avecia. The development of new reagents and processes are described in this communication.
Description: 2297-2304
URI: http://hdl.handle.net/123456789/6695
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.45B(10) [October 2006]

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