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IJC-B Vol.45B(09) [September 2006] >


Title: Antimicrobial activity of 1-[p{3'-(2'-aryl- 4-oxo-1',3'-thiazolyl)} diphenyl]/[3'-(2'-aryl-4-oxo-1',3'-thiazolyl)]-2-phenyl- 4-cyclohexylidene imidazol-5-ones
Authors: Bishnoi, Abha
Srivastava, Krishna
Tripathi, C K M
Keywords: Oxozolone
hippuric acid
cyclohexane
acetic anhydride
imidazole
thioglycollic acid
Issue Date: Sep-2006
Publisher: CSIR
IPC CodeInt. Cl.8 C07D
Abstract: 2-Phenyl-4-cyclohexylidene-1,3-oxozol-5-one 1 has been obtained from the condensation of hippuric acid and cyclohexane using acetic anhydride. The compound 1 is then converted to its respective imidazoles 2 and 3 by condensing with benzidene and hydrazine hydrate. Which on heating with different aromatic aldehydes give 1-(p-arylidene-amino-diphenyl)/(arylidene-amino)-2-phenyl-4-cycohexlyidene imidazol-5-one 4 and 5. Interaction of 4 and 5 with thioglycollic acid undergo cyclization to give titled compounds 6 and 7. The new compounds have been screened for their antimicrobial activity.
Page(s): 2136-2139
ISSN: 0975-0983(Online); 0376-4699(Print)
Source:IJC-B Vol.45B(09) [September 2006]

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