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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.45B [2006] >
IJC-B Vol.45B(09) [September 2006] >
| Title: | Antimicrobial activity of 1-[p{3'-(2'-aryl- 4-oxo-1',3'-thiazolyl)} diphenyl]/[3'-(2'-aryl-4-oxo-1',3'-thiazolyl)]-2-phenyl- 4-cyclohexylidene imidazol-5-ones |
| Authors: | Bishnoi, Abha
Srivastava, Krishna
Tripathi, C K M |
| Keywords: | Oxozolone
hippuric acid
cyclohexane
acetic anhydride
imidazole
thioglycollic acid |
| Issue Date: | Sep-2006 |
| Publisher: | CSIR |
| IPC Code: | Int. Cl.8 C07D |
| Abstract: | 2-Phenyl-4-cyclohexylidene-1,3-oxozol-5-one 1 has been obtained from the condensation of hippuric acid and cyclohexane using acetic anhydride. The compound 1 is then converted to its respective imidazoles 2 and 3 by condensing with benzidene and hydrazine hydrate. Which on heating with different aromatic aldehydes give 1-(p-arylidene-amino-diphenyl)/(arylidene-amino)-2-phenyl-4-cycohexlyidene imidazol-5-one 4 and 5. Interaction of 4 and 5 with thioglycollic acid undergo cyclization to give titled compounds 6 and 7. The new compounds have been screened for their antimicrobial activity. |
| Page(s): | 2136-2139 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Source: | IJC-B Vol.45B(09) [September 2006]
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