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IJC-B Vol.46B(07) [July 2007] >

Title: Environmentally benign synthesis of fluorinated pyrazolone derivatives and their antimicrobial activity
Authors: Shelke, S N
Dalvi, N R
Kale, S B
More, M S
Gill, C H
Karale, B K
Keywords: Fluorinated compound
4-Formyl pyrazole
Issue Date: Jul-2007
Publisher: CSIR
Abstract: Various fluorine containing 4-[-3-(4-aryl)-1-phenyl-1H-pyrazol-4-yl)methylene]-3-(trifluoromethyl)-1-phenyl-1H-pyrazol-5(4H)-one 3a-g and 3-(trifluoromethyl)-4-(4-oxo-4H-chromon-3-yl)methylene-1-phenyl-1H-pyrazol-5(4H)-one 5a-k have been synthesized by conventional and non-conventional method. The synthesis 3 and 5 highlights a comparative study of conventional, ultrasonication and microwave techniques. All products have been characterized by IR, ¹H NMR, MS study and screened for their antimicrobial activity.
Page(s): 1174-1178
ISSN: 0376-4699
Source:IJC-B Vol.46B(07) [July 2007]

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