NISCAIR Online Periodicals Repository

NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR)  >
NISCAIR PUBLICATIONS >
Research Journals >
Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.45B [2006] >
IJC-B Vol.45B(09) [September 2006] >


Title: Synthesis of [2-(3-oxo-3,4-dihydro-2H-benzo[1,4]oxazin-6- carbonyl)-1H-indol-3-yl]acetic acids as potential COX-2 inhibitors
Authors: Dubey, P K
Kumar, T Venkateshwar
Reddanna, P
Kumar, K Anil
Keywords: COX-2 inihibitors
inflammation
acrylic acid methylester
indole acetic acid
benzoxazinone
Issue Date: Sep-2006
Publisher: CSIR
IPC CodeInt.Cl.8 C07D
Abstract: The synthesis of potential COX-2 inhibitors by means of internal Michael addition of ortho toluenesulfonylaminophenyl acrylic acid methyl esters 5a-d with 6-(chloroacetyl)-2H-1,4-bezoxazin-4H-ones 6a-c followed by hydrolysis resulting in the formation of [2-(3-oxo-3,4-dihydro-2H-benzo[1,4]oxazin-6-carbonyl)-1H-indol-3-yl]acetic acids 1a-k are reported.
Page(s): 2128-2132
ISSN: 0975-0983(Online); 0376-4699(Print)
Source:IJC-B Vol.45B(09) [September 2006]

Files in This Item:

File Description SizeFormat
IJCB 45B(9) 2128-2132.pdf154.57 kBAdobe PDFView/Open
 Current Page Visits: 427 
Recommend this item

 

National Knowledge Resources Consortium |  NISCAIR Website |  Contact us |  Feedback

Disclaimer: NISCAIR assumes no responsibility for the statements and opinions advanced by contributors. The editorial staff in its work of examining papers received for publication is helped, in an honorary capacity, by many distinguished engineers and scientists.

CC License Except where otherwise noted, the Articles on this site are licensed under Creative Commons License: CC Attribution-Noncommercial-No Derivative Works 2.5 India

Copyright © 2012 The Council of Scientific and Industrial Research, New Delhi. All rights reserved.

Powered by DSpace Copyright © 2002-2007 MIT and Hewlett-Packard | Compliant to OAI-PMH V 2.0

Home Page Total Visits: 510136 since 06-Feb-2009  Last updated on 11-Apr-2014Webmaster: nopr@niscair.res.in