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Indian Journal of Experimental Biology (IJEB) >
IJEB Vol.44 [2006] >
IJEB Vol.44(12) [December 2006] >
| Title: | In vitro antioxidant studies of Sphaeranthus indicus (Linn) |
| Authors: | Shirwaikar, Annie Prabhu, Kirti S Punitha, I S R |
| Keywords: | Antioxidant Free radicals Sphaeranthus indicus |
| Issue Date: | Dec-2006 |
| Publisher: | CSIR |
| Abstract: | The free radical scavenging potential of the
plant S.indicus was studied by using
different antioxidant models of screening. The ethanolic extract at 1000 g/ml showed maximum scavenging of the radical cation, 2,2-azinobis-(3-ethylbenzothiazoline-6-sulphonate)
(ABTS) observed upto 41.99 % followed by the scavenging of the stable radical
1,1-diphenyl, 2-picryl hydrazyl (DPPH) (33.27 %), superoxide dismutase (25.14
%) and nitric oxide radical (22.36 %) at the same concentration. However, the
extract showed only moderate scavenging activity of iron chelation (14.2 %).
Total antioxidant capacity of the extract was found to be 160.85 nmol/g
ascorbic acid. The results justify the therapeutic applications of the plant in
the indigenous system of medicine, augmenting its therapeutic value. |
| Page(s): | 993-996 |
| ISSN: | 0975-1009 (Online); 0019-5189 (Print) |
| Source: | IJEB Vol.44(12) [December 2006]
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