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IJEB Vol.44(12) [December 2006] >


Title: In vitro antioxidant studies of Sphaeranthus indicus (Linn)
Authors: Shirwaikar, Annie
Prabhu, Kirti S
Punitha, I S R
Keywords: Antioxidant
Free radicals
Sphaeranthus indicus
Issue Date: Dec-2006
Publisher: CSIR
Abstract: The free radical scavenging potential of the plant S.indicus was studied by using different antioxidant models of screening. The ethanolic extract at 1000 g/ml showed maximum scavenging of the radical cation, 2,2-azinobis-(3-ethylbenzothiazoline-6-sulphonate) (ABTS) observed upto 41.99 % followed by the scavenging of the stable radical 1,1-diphenyl, 2-picryl hydrazyl (DPPH) (33.27 %), superoxide dismutase (25.14 %) and nitric oxide radical (22.36 %) at the same concentration. However, the extract showed only moderate scavenging activity of iron chelation (14.2 %). Total antioxidant capacity of the extract was found to be 160.85 nmol/g ascorbic acid. The results justify the therapeutic applications of the plant in the indigenous system of medicine, augmenting its therapeutic value.
Page(s): 993-996
ISSN: 0975-1009 (Online); 0019-5189 (Print)
Source:IJEB Vol.44(12) [December 2006]

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