|
NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR) >
NISCAIR PUBLICATIONS >
Research Journals >
Indian Journal of Experimental Biology (IJEB) >
IJEB Vol.44 [2006] >
IJEB Vol.44(12) [December 2006] >
| Title: | Antigenic competition among different ‘O’ antigens of Salmonella enterica subspecies enterica serovars during hyperimmunization in pony mares |
| Authors: | Singh, B R
Chandra, Mudit
Agrawal, Ravi Kant
Nagrajan, Babu |
| Keywords: | Antigenic competition
Equines
‘O’ antigens
Salmonella |
| Issue Date: | Dec-2006 |
| Publisher: | CSIR |
| Abstract: | The present study on antigenic competition
among somatic ‘O’ antigens of different Salmonella
groups (A, B, C1, C2, D and E1) in mares revealed that the immune response to
most of the antigens was not (A, B, C2) or little (C1, D) affected by antigenic
competition. However, E1 group antigen, which induced high antibody titres
(Avg. 12967.3) when given alone, produced almost 3.5 log2 lower
antibody titres on giving with other antigens, indicating the antigenic
competition among some Salmonella
group antigens. The antigenic competition varied for different antigens even of
the similar chemical nature. Therefore, antigens belonging to different somatic
groups should not be given together for the purpose of raising polyvalent serum
or for immunization using multivalent Salmonella
vaccines prepared from strains of different ‘O’ groups revealing antigenic
competition. |
| Page(s): | 1022-1025 |
| ISSN: | 0975-1009 (Online); 0019-5189 (Print) |
| Source: | IJEB Vol.44(12) [December 2006]
|
|
