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Title: Antihyperglycemic, antistress and nootropic activity of roots of Rubia cordifolia Linn
Authors: Patil, Rupali A
Jagdale, Swati C
Kasture, Sanjay B
Keywords: Antihyperglycemic activity
Nootropic activity
Roof extract
Rubia Cordifolia
Issue Date: Dec-2006
Publisher: CSIR
Abstract: Effect of alcoholic extract of roots of Rubia cordifolia was studied on elevated blood glucose level in alloxan treated animals. The extract reduced the blood sugar level raised by alloxan. Effect of alcoholic extract was also investigated on cold restraint induced stress and on scopolamine-induced memory impairment. Alcoholic extract enhanced brain γ-amino-n-butyric acid (GABA) levels and decreased brain dopamine and plasma corticosterone levels. Acidity and ulcers caused due to cold restraint stress were inhibited by alcoholic extract. Animals treated with alcoholic extract spent more time in open arm in elevated plus maze model. It also antagonized scopolamine induced learning and memory impairment. Baclofen induced catatonia was potentiated by alcoholic extract.
Description: 987-992
ISSN: 0975-1009 (Online); 0019-5189 (Print)
Appears in Collections:IJEB Vol.44(12) [December 2006]

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