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Research Journals >
Indian Journal of Experimental Biology (IJEB) >
IJEB Vol.44 [2006] >
IJEB Vol.44(12) [December 2006] >
| Title: | Antihyperglycemic, antistress and nootropic activity of roots of Rubia cordifolia Linn |
| Authors: | Patil, Rupali A
Jagdale, Swati C
Kasture, Sanjay B |
| Keywords: | Antihyperglycemic activity
Antistress
Nootropic activity
Roof extract
Rubia Cordifolia |
| Issue Date: | Dec-2006 |
| Publisher: | CSIR |
| Abstract: | Effect of
alcoholic extract of roots of Rubia
cordifolia was studied on elevated blood glucose level in alloxan treated
animals. The extract reduced the blood sugar level raised by alloxan. Effect of
alcoholic extract was also investigated on cold restraint induced stress and on
scopolamine-induced memory impairment. Alcoholic extract enhanced brain
γ-amino-n-butyric acid (GABA) levels and decreased brain dopamine and plasma
corticosterone levels. Acidity and ulcers caused due to cold restraint stress
were inhibited by alcoholic extract. Animals treated with alcoholic extract
spent more time in open arm in elevated plus maze model. It also antagonized
scopolamine induced learning and memory impairment. Baclofen induced catatonia
was potentiated by alcoholic extract. |
| Page(s): | 987-992 |
| ISSN: | 0975-1009 (Online); 0019-5189 (Print) |
| Source: | IJEB Vol.44(12) [December 2006]
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