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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.46B [2007] >
IJC-B Vol.46B(04) [April 2007] >
| Title: | Synthesis and evaluation of some 1, 4-dihydropyridine and their derivatives as antihypertensive agents |
| Authors: | Pattan, Shashikant R
Rasal, V P
VVenkatramana, N
Khade, A B
Butle, S R
Jadhav, S G
Desai, B G
Manvi, F V |
| Keywords: | Antihypertensive
Vasodilators
Antidiabetic
Antitumour
Antimicrobial |
| Issue Date: | Apr-2007 |
| Publisher: | CSIR |
| IPC Code: | Int. Cl. ⁸ C07D |
| Abstract: | A series of 1, 4-dihydro-2, 6-dimethyl-4-{4-[3-(2-aminopyrazine/1-amino-4-methyl piperazine)-2-hydroxy propoxy]-phenyl}-pyridine-3, 5-carbamoyl have been synthesized and the structure of the compounds have been confirmed by IR, ¹H NMR , MS & elemental analysis. The title compounds have been evaluated for antihypertensive activity by tail-cuff method. Some of these compounds have been found to exhibit excellent antihypertensive activity. |
| Page(s): | 698-701 |
| ISSN: | 0376-4699 |
| Source: | IJC-B Vol.46B(04) [April 2007]
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