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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.45B [2006] >
IJC-B Vol.45B(07) [July 2006] >
| Title: | Isomerization of the Baylis-Hillman adducts using amberlyst-15 as a heterogeneous reusable catalyst: a simple and efficient stereoselective synthesis of (E)-cinnamyl alcohol derivatives |
| Authors: | Das, Biswanath
Banerjee, Joydeep
Majhi, Anjoy
Chowdhury, Nikhil
Venkateswarlu, Katta
Holla, Harish |
| Keywords: | Baylis-Hillman adduct
cinnamyl alcohol
Amberlyst-15
isomerization
stereoselective synthesis
heterogeneous reusable catalyst |
| Issue Date: | Jul-2006 |
| Publisher: | CSIR |
| IPC Code: | Int.Cl.8C07C |
| Abstract: | The Baylis-Hillman adducts, 3-aryl-3-hydroxy-2-methylene-alkanoates and 3-aryl-3-hydroxy-2-methylene-alkanenitriles have been efficiently isomerized to the corresponding (E)-cinnamyl alcohols by treatment of the adducts with Ac2O in the presence of Amberlyst-15 followed by hydrolysis of the intermediate acetates with K2CO3/MeOH. The first step occurs under solvent-free conditions and the catalyst has been found to be reusable. |
| Page(s): | 1729-1733 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Source: | IJC-B Vol.45B(07) [July 2006]
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