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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.45B [2006] >
IJC-B Vol.45B(07) [July 2006] >
| Title: | Synthesis and studies of novel homoveratryl based thiohydantoins as antibacterial as well as anti-HIV agents |
| Authors: | Patel, R B
Desai, K R
Chikhalia, K H |
| Keywords: | Homoveratrylamine
thiohydantoin
styrylation
antibacterial activity
anti-HIV activity |
| Issue Date: | Jul-2006 |
| Publisher: | CSIR |
| IPC Code: | Int.Cl.8C07D |
| Abstract: | N,N′-bis(3,4-dimethoxyphenylethyl)-5-(arylidene)-2-thiohydantoins 3a-j have been prepared by condensation of 1,3-diaryl-2-thiohydantoin 2 with various aromatic aldehydes. The compound 2 has been prepared by the reaction of N,N′-bis(3,4-dimethoxyphenylethyl)thiourea 1 with chloroaceticacid. The compounds have been tested for their antibacterial and anti-HIV activities against different microorganisms. The structures of novel synthesized compounds have been established on the basis of elemental analyses, 1H NMR, IR and mass spectral data. |
| Page(s): | 1716-1721 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Source: | IJC-B Vol.45B(07) [July 2006]
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