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Title: Synthesis and studies of novel homoveratryl based thiohydantoins as antibacterial as well as anti-HIV agents
Authors: Patel, R B
Desai, K R
Chikhalia, K H
Keywords: Homoveratrylamine;thiohydantoin;styrylation;antibacterial activity;anti-HIV activity
Issue Date: Jul-2006
Publisher: CSIR
IPC Code: Int.Cl.8C07D
Abstract: N,N′-bis(3,4-dimethoxyphenylethyl)-5-(arylidene)-2-thiohydantoins 3a-j have been prepared by condensation of 1,3-diaryl-2-thiohydantoin 2 with various aromatic aldehydes. The compound 2 has been prepared by the reaction of N,N′-bis(3,4-dimethoxyphenylethyl)thiourea 1 with chloroaceticacid. The compounds have been tested for their antibacterial and anti-HIV activities against different microorganisms. The structures of novel synthesized compounds have been established on the basis of elemental analyses, 1H NMR, IR and mass spectral data.
Page(s): 1716-1721
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.45B(07) [July 2006]

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