Please use this identifier to cite or link to this item:
Title: Synthesis of novel substituted / unsubstituted- (2,8-bis-trifluoromethyl-quinolin-4-yloxy)-acetic acid: Derivatives of cephalosporin and their antibacterial activity
Authors: Singh, Santosh Kumar
Nahta, Ajay
Tiwari, R P
Jain, Praveen
Keywords: Quinolinoxy acetic acids;cephalosporins;substituted cephalosporanic acids;hexamethyldisilazane;chloro¬≠rimethylsilane;silylation;antibacterial activity
Issue Date: Jul-2006
Publisher: CSIR
IPC Code: Int.Cl.8C07D
Abstract: Substituted/unsubstituted-(2,8-bis-trifluoromethyl-quinolin-4-yloxy)-acetic acid derivatives of cephalosporin have been synthesized by condensation of acid chlorides of substituted/unsubstituted - (2,8-bis-trifluoromethyl-quinolin-4-yloxy)-acetic acid with various silylated (6R,7R)-7-amino-3-substituted cephalosporanic acids. The products have been tested for their antibacterial activity.
Page(s): 1734-1739
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.45B(07) [July 2006]

Files in This Item:
File Description SizeFormat 
IJCB 45B(7) 1734-1739.pdf125.98 kBAdobe PDFView/Open

Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.