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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.45B [2006] >
IJC-B Vol.45B(07) [July 2006] >
| Title: | Synthesis of novel substituted / unsubstituted- (2,8-bis-trifluoromethyl-quinolin-4-yloxy)-acetic acid: Derivatives of cephalosporin and their antibacterial activity |
| Authors: | Singh, Santosh Kumar
Nahta, Ajay
Tiwari, R P
Jain, Praveen |
| Keywords: | Quinolinoxy acetic acids
cephalosporins
substituted cephalosporanic acids
hexamethyldisilazane
chlororimethylsilane
silylation
antibacterial activity |
| Issue Date: | Jul-2006 |
| Publisher: | CSIR |
| IPC Code: | Int.Cl.8C07D |
| Abstract: | Substituted/unsubstituted-(2,8-bis-trifluoromethyl-quinolin-4-yloxy)-acetic acid derivatives of cephalosporin have been synthesized by condensation of acid chlorides of substituted/unsubstituted - (2,8-bis-trifluoromethyl-quinolin-4-yloxy)-acetic acid with various silylated (6R,7R)-7-amino-3-substituted cephalosporanic acids. The products have been tested for their antibacterial activity. |
| Page(s): | 1734-1739 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Source: | IJC-B Vol.45B(07) [July 2006]
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