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Title: Microwave assisted facile synthesis of amino pyrimidines bearing benzofuran and investigation of their antimicrobial activity
Authors: Kumar, D B Aruna
Prakash, G K
Kumaraswamy, M N
Nandeshwarappa, B P
Sherigara, B S
Mahadevan, K M
Keywords: Benzofuran;chalcones;guanidine hydrochloride;amino pyrimidines;antimicrobial activity
Issue Date: Jul-2006
Publisher: CSIR
IPC Code: Int.Cl.8 C07D
Abstract: 2-acetylbenzofuran on treatment with substituted aldehydes under solvent free microwave irradiation affords the corresponding chalcones 2a-e. The compounds 2a-e on reaction with guanidine hydrochloride under microwave irradiation produce 3a-e. The structures of the newly synthesized compounds have been established by elemental analysis and spectral data. The compounds 3a-e have been evaluated for their antimicrobial activity.
Page(s): 1699-1703
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.45B(07) [July 2006]

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