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Title: Synthesis of <i>N</i>-3(4-(4-chlorophenyl thiazole-2-yl)-(2-(amino)methyl)-quinazoline-4(3<i style="">H</i>)-one and their derivatives for antitubercular activity
Authors: Pattan, Shashikant R
Reddy, V V Krishna
Manvi, F V
Desai, B G
Bhat, A R
Keywords: Mycobacterial activity
Issue Date: Jul-2006
Publisher: CSIR
Series/Report no.: <b>Int.Cl.<sup>8</sup> C07D</b>
Abstract: A new series of <i style="">N</i>-3[4-(4-chlorophenyl thiazole-2-yl)-2-amino methyl] quinazoline-4(3<i style="">H</i>)-one and their derivatives are synthesized. The structures of the title compounds are confirmed on the basis of IR and <sup>1</sup>H NMR. The compounds are screened for their antitubercular activity, using H<sub>37</sub>Rv strain on L J medium. All the compounds have showed moderate to promising antitubercular activity.
Description: 1778-1781
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.45B(07) [July 2006]

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