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Title: Studies in the synthesis of 2-mercapto-5-methoxybenzimidazole
Authors: Mahajan, S S
Nandre, R G
Keywords: Mercapto-5-methoxybenzimidazole;omeprazole
Issue Date: Jul-2006
Publisher: CSIR
IPC Code:  Int.Cl.8C07D
Abstract: The compound, 2-mercapto-5-methoxybenzimidazole, is an important intermediate required for the synthesis of omeprazole. It is a proton pump blocker or an inhibitor of the enzyme, H+/K+- ATPase. In the present work, synthesis of this intermediate by three different routes has been discussed and its yields from all the three routes have been compared.
Page(s): 1756-1758
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.45B(07) [July 2006]

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