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Indian Journal of Experimental Biology (IJEB) >
IJEB Vol.44 [2006] >
IJEB Vol.44(08) [August 2006] >
| Title: | Modulation of gastric mucosal mast cell population : Role of vestibulo cerebellar lesion |
| Authors: | Sarkar, Nita
Purkayastha, Sudarshana
Sarkar, Biswarup
Guha, Debjani |
| Keywords: | Cerebellar lesion
Cerebellum
Gastric mucosal mast cell
Histamine
Ulcer |
| Issue Date: | Aug-2006 |
| Publisher: | CSIR |
| Abstract: | Posterior cerebellar lesion induced severe
focal inflammatory ulcers at the stomach associated with extensive damage of
the surface epithelial cells, leading to focal necrotic ulcers. The ulcer index
increased maximally and progressively between day 7 and day 14 after lesion.
The total mucosal mast cell and degranulated mucosal mast cell increased
maximally on day 7 and progressively declined from day 14 to day 21. Gastric
histamine content was also significantly increased on day 7 and 14. A
significant reduction in mucous content (total CHO:P) was observed within 7-28
days after lesion. The results suggest that the gastric mucosal mast cells play
an important role in ulcerogenesis induced by cerebellar lesion. |
| Page(s): | 627-634 |
| ISSN: | 0975-1009 (Online); 0019-5189 (Print) |
| Source: | IJEB Vol.44(08) [August 2006]
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