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Title: Effect of radish (Raphanus sativus Linn.) on thyroid status under conditions of varying iodine intake in rats
Authors: Chandra, Amar K
Mukhopadhyay, Sanjukta
Ghosh, Dishari
Tripathy, Smritiratan
Keywords: Glucosinolates;Iodine;Radish (Rapanus sativus);Thyroid hormone;Thyroid peroxidase;Urinary iodine;Urinary thiocyanate
Issue Date: Aug-2006
Publisher: CSIR
Abstract: Cruciferous plants viz. cabbage, cauliflower, turnip, radish, mustard etc. that contain goitrogenic/antithyroid substances, constitute a portion of regular human diet. The effect of chronic feeding of fresh and cooked radish, R. sativus under varying state of iodine intake on morphological and functional status of thyroid in albino rats was evaluated by thyroid gland morphology and histology, thyroid peroxidase activity, serum triiodothyronine, thyroxine and thyrotropin levels. The consumption pattern of iodine and goitrogens of cyanogenic origin was evaluated by measuring urinary iodine and thiocyanate levels respectively. After chronic radish feeding, increased weight of thyroid gland, decreased thyroid peroxidase activity, reduced thyroid hormone profiles and elevated level of thyrotropin were observed resembling a relative state of hypoactive thyroid gland in comparison to control even after supplementation of adequate iodine.
Page(s): 653-661
ISSN: 0975-1009 (Online); 0019-5189 (Print)
Appears in Collections:IJEB Vol.44(08) [August 2006]

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