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NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR) >
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Research Journals >
Indian Journal of Experimental Biology (IJEB) >
IJEB Vol.44 [2006] >
IJEB Vol.44(06) [June 2006] >
| Title: | Antioxidant and antiulcer activity of aqueous extract of a polyherbal formulation |
| Authors: | Shirwaikar, Annie
Ram, H N Aswatha
Mohapatra, P |
| Keywords: | Alcohol
Antioxidant
Anti-ulcer
Hingwashtak churna
Ibuprofen |
| Issue Date: | Jun-2006 |
| Publisher: | CSIR |
| Abstract: | The aqueous extract of Hingwashtak churna was evaluated for
gastroprotection in rats using the ibuprofen and ethanol induced ulcer models.
Efficacy was assessed by determination of mean ulcer size, ulcer number and
ulcer index. Oral administration of the aqueous extract (750 mg/kg)
significantly protected against gastric lesions by 84.96% and 91.12% as
compared to ranititidine (95.54 and 95.2%) in the ibuprofen and alcohol induced
ulcer models respectively. The findings suggest that the significant
gastroprotective activity could be mediated by its antioxidant activity which
was evaluated by using different antioxidant models of screening. |
| Page(s): | 474-480 |
| ISSN: | 0975-1009 (Online); 0019-5189 (Print) |
| Source: | IJEB Vol.44(06) [June 2006]
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